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Pharmacologic treatment with CPI-613 and PS48 decreases mitochondrial  membrane potential and increases quantity of autolysosomes in porcine  fibroblasts | Scientific Reports
Pharmacologic treatment with CPI-613 and PS48 decreases mitochondrial membrane potential and increases quantity of autolysosomes in porcine fibroblasts | Scientific Reports

The Pyruvate Dehydrogenase Complex in Cancer: Implications for the  Transformed State and Cancer Chemotherapy | IntechOpen
The Pyruvate Dehydrogenase Complex in Cancer: Implications for the Transformed State and Cancer Chemotherapy | IntechOpen

Prolongation of survival induced by four doses of CPI-613 (25 mg/kg),... |  Download Scientific Diagram
Prolongation of survival induced by four doses of CPI-613 (25 mg/kg),... | Download Scientific Diagram

Cornerstone Pharmaceuticals Lead Compound CPI-613
Cornerstone Pharmaceuticals Lead Compound CPI-613

A strategically designed small molecule attacks alpha-ketoglutarate  dehydrogenase in tumor cells through a redox process | SpringerLink
A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process | SpringerLink

CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via  the AMPK-ACC signaling | Journal of Experimental & Clinical Cancer Research  | Full Text
CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via the AMPK-ACC signaling | Journal of Experimental & Clinical Cancer Research | Full Text

Mitochondria in cancer metabolism, an organelle whose time has come? -  Abstract - Europe PMC
Mitochondria in cancer metabolism, an organelle whose time has come? - Abstract - Europe PMC

Selectively Targeting Metabolism in Mitochondria In Cancer Cells | Cancer  Biology
Selectively Targeting Metabolism in Mitochondria In Cancer Cells | Cancer Biology

Devimistat - Wikipedia
Devimistat - Wikipedia

CPI-613 Supplier | CAS 95809-78-2 | Focus Biomolecules
CPI-613 Supplier | CAS 95809-78-2 | Focus Biomolecules

Devimistat - Wikipedia
Devimistat - Wikipedia

A comprehensive analysis of clinical trials in pancreatic cancer: what is  coming down the pike? | Oncotarget
A comprehensive analysis of clinical trials in pancreatic cancer: what is coming down the pike? | Oncotarget

A Phase II Clinical Trial of CPI-613 in Patients with Relapsed or  Refractory Small Cell Lung Carcinoma
A Phase II Clinical Trial of CPI-613 in Patients with Relapsed or Refractory Small Cell Lung Carcinoma

A phase I study of the first-in-class antimitochondrial metabolism agent,  CPI-613, in patients with advanced hematologic malignancies. - Abstract -  Europe PMC
A phase I study of the first-in-class antimitochondrial metabolism agent, CPI-613, in patients with advanced hematologic malignancies. - Abstract - Europe PMC

Finding Targets in Cancer's Metabolic Quirks
Finding Targets in Cancer's Metabolic Quirks

Devimistat (CPI-613) | デヒドロゲナーゼ 阻害剤
Devimistat (CPI-613) | デヒドロゲナーゼ 阻害剤

Devimistat | CPI-613 | CAS#95809-78-2 | Antineoplastic | MedKoo Biosciences
Devimistat | CPI-613 | CAS#95809-78-2 | Antineoplastic | MedKoo Biosciences

An integrated in vivo and in silico analysis of the metabolism disrupting  effects of CPI-613 on embryo-larval zebrafish (Danio rerio) - ScienceDirect
An integrated in vivo and in silico analysis of the metabolism disrupting effects of CPI-613 on embryo-larval zebrafish (Danio rerio) - ScienceDirect

The Mitochondrion as an Emerging Therapeutic Target in Cancer: Trends in  Molecular Medicine
The Mitochondrion as an Emerging Therapeutic Target in Cancer: Trends in Molecular Medicine

Predictive targeting of mitochondrial metabolism in Acute Myeloid Leukemia  patients with a lipoic acid analog | medRxiv
Predictive targeting of mitochondrial metabolism in Acute Myeloid Leukemia patients with a lipoic acid analog | medRxiv

CPI-613 | CAS:95809-78-2 | PDH/α-KGDH inhibitor | High Purity |  Manufacturer BioCrick
CPI-613 | CAS:95809-78-2 | PDH/α-KGDH inhibitor | High Purity | Manufacturer BioCrick

Predictive targeting of mitochondrial metabolism in Acute Myeloid Leukemia  patients with a lipoic acid analog | medRxiv
Predictive targeting of mitochondrial metabolism in Acute Myeloid Leukemia patients with a lipoic acid analog | medRxiv

Cancers | Free Full-Text | The Metabolic Inhibitor CPI-613 Negates  Treatment Enrichment of Ovarian Cancer Stem Cells
Cancers | Free Full-Text | The Metabolic Inhibitor CPI-613 Negates Treatment Enrichment of Ovarian Cancer Stem Cells

CPI-613 (Devimistat) | ≥99%(HPLC) | Dehydrogenase Inhibitor | AdooQ®
CPI-613 (Devimistat) | ≥99%(HPLC) | Dehydrogenase Inhibitor | AdooQ®

Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox  inhibitors as a potential strategy to abrogate tumor cell proliferation |  Scientific Reports
Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation | Scientific Reports