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Prämedikation Komplexität Beispiel proton sponge mechanism Treibstoff Spule Überprüfung

1,8-Bis(dimethylamino)naphthalene - Wikipedia
1,8-Bis(dimethylamino)naphthalene - Wikipedia

Figure 4: Schematic of the proton-sponge mechanism.
Figure 4: Schematic of the proton-sponge mechanism.

The great escape: how cationic polyplexes overcome the endosomal barrier -  Journal of Materials Chemistry B (RSC Publishing)
The great escape: how cationic polyplexes overcome the endosomal barrier - Journal of Materials Chemistry B (RSC Publishing)

Nanomaterials | Free Full-Text | Tailoring Iron Oxide Nanoparticles for  Efficient Cellular Internalization and Endosomal Escape | HTML
Nanomaterials | Free Full-Text | Tailoring Iron Oxide Nanoparticles for Efficient Cellular Internalization and Endosomal Escape | HTML

Enabling cytoplasmic delivery and organelle targeting by surface  modification of nanocarriers | Nanomedicine
Enabling cytoplasmic delivery and organelle targeting by surface modification of nanocarriers | Nanomedicine

Pharmaceutics | Free Full-Text | The Multifaceted Histidine-Based Carriers  for Nucleic Acid Delivery: Advances and Challenges | HTML
Pharmaceutics | Free Full-Text | The Multifaceted Histidine-Based Carriers for Nucleic Acid Delivery: Advances and Challenges | HTML

Theranostics 04: 0240 image No. 005
Theranostics 04: 0240 image No. 005

a) Schematic illustration of the proton sponge effect leading to siRNA... |  Download Scientific Diagram
a) Schematic illustration of the proton sponge effect leading to siRNA... | Download Scientific Diagram

Endosomal Escape Pathways for Non-Viral Nucleic Acid Delivery Systems |  IntechOpen
Endosomal Escape Pathways for Non-Viral Nucleic Acid Delivery Systems | IntechOpen

Nanocarrier‐Mediated Cytosolic Delivery of Biopharmaceuticals - He - 2020 -  Advanced Functional Materials - Wiley Online Library
Nanocarrier‐Mediated Cytosolic Delivery of Biopharmaceuticals - He - 2020 - Advanced Functional Materials - Wiley Online Library

PDF] Endosomal Size and Membrane Leakiness Influence Proton Sponge-Based  Rupture of Endosomal Vesicles. | Semantic Scholar
PDF] Endosomal Size and Membrane Leakiness Influence Proton Sponge-Based Rupture of Endosomal Vesicles. | Semantic Scholar

Proton Sponge Analogue of the Tröger's Base: A Compound with Remarkable  Enantiomeric Stability - Ozeryanskii - 2017 - ChemistrySelect - Wiley  Online Library
Proton Sponge Analogue of the Tröger's Base: A Compound with Remarkable Enantiomeric Stability - Ozeryanskii - 2017 - ChemistrySelect - Wiley Online Library

Hypothetical mechanisms of endosomal escape: in the proton-sponge model...  | Download Scientific Diagram
Hypothetical mechanisms of endosomal escape: in the proton-sponge model... | Download Scientific Diagram

The combination endosomal lysis mechanism. Both the proton sponge... |  Download Scientific Diagram
The combination endosomal lysis mechanism. Both the proton sponge... | Download Scientific Diagram

Naphthalene proton sponges as hydride donors: diverse appearances of the  tert -amino-effect - Organic & Biomolecular Chemistry (RSC Publishing)  DOI:10.1039/C0OB00899K
Naphthalene proton sponges as hydride donors: diverse appearances of the tert -amino-effect - Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C0OB00899K

Fine-tuning of proton sponges by precise diaminoethanes and histidines in  pDNA polyplexes - ScienceDirect
Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes - ScienceDirect

Figure 5 | Brain-Targeted Polymers for Gene Delivery in the Treatment of  Brain Diseases | SpringerLink
Figure 5 | Brain-Targeted Polymers for Gene Delivery in the Treatment of Brain Diseases | SpringerLink

1,8-Bis(dimethylamino)naphthalene - Wikipedia
1,8-Bis(dimethylamino)naphthalene - Wikipedia

Super-resolution Imaging of Proton Sponge-Triggered Rupture of Endosomes  and Cytosolic Release of Small Interfering RNA | ACS Nano
Super-resolution Imaging of Proton Sponge-Triggered Rupture of Endosomes and Cytosolic Release of Small Interfering RNA | ACS Nano

Diagram of the proton sponge effect: particles coated with... | Download  Scientific Diagram
Diagram of the proton sponge effect: particles coated with... | Download Scientific Diagram

Rational modification of oligoarginine for highly efficient siRNA delivery:  structure–activity relationship and mechanism of intracellular trafficking  of siRNA - ScienceDirect
Rational modification of oligoarginine for highly efficient siRNA delivery: structure–activity relationship and mechanism of intracellular trafficking of siRNA - ScienceDirect

PDF] The proton sponge hypothesis: Fable or fact? | Semantic Scholar
PDF] The proton sponge hypothesis: Fable or fact? | Semantic Scholar

Polymers | Free Full-Text | Chitosan in Non-Viral Gene Delivery: Role of  Structure, Characterization Methods, and Insights in Cancer and Rare  Diseases Therapies | HTML
Polymers | Free Full-Text | Chitosan in Non-Viral Gene Delivery: Role of Structure, Characterization Methods, and Insights in Cancer and Rare Diseases Therapies | HTML